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GUERIN'S PHARMACY SOUTH CAROLINA’S OLDEST PHARMACY

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Serving Summerville and Dorchester County since 1871

Welcome to Guerin's Pharmacy

Guerin’s Pharmacy, located in the heart of downtown Summerville, South Carolina, is the oldest drugstore in the state and has proudly operated as an independent apothecary since 1871. Serving Dorchester County and the surrounding Lowcountry for generations, the pharmacy has remained dedicated to personal care and trusted service.

Founded during the Civil War era, Guerin’s Pharmacy traces its roots to Dr. Schwettman, a Charleston pharmacist who relocated his business to Summerville during the war. After completing his military service, Dr. Henry C. Guerin purchased the Summerville location, establishing what would become a long-standing community drugstore deeply woven into the history and daily life of Summerville and Dorchester County.

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Are you ready for a treat?

Craving some ice cream? The soda fountain at Guerin’s Pharmacy serves up delicious treats for Summerville and Dorchester County. Visit us today!
Soda Fountain

Who's that pharmacist?

Guerin’s Pharmacy has proudly served Summerville, SC and Dorchester County since 1871. As the oldest pharmacy in South Carolina, we invite you to visit our legendary candy counter!
About Us

Need to refill your meds?

Whether you need a prescription filled, are searching for a gift, or want a refreshing soda, Guerin’s Pharmacy proudly serves Summerville, SC and Dorchester County.
Our Services

Great Customer Service

 
 
 
 
 
 
 
  
 
 
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 Alison Goheen profile picture 
 
 
 Alison Goheen 
 
 
 
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It's a challenge to find same day pet meds but Guerin's can.  The staff was very helpful and explained how to give to my cats the medicine.
  
 
  
 
 
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 Tom Ryan profile picture 
 
 
 Tom Ryan 
 
 
 
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One of the few pharmacies that offers compounding Rx.
  
 
  
 
 
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 Robert Velarde profile picture 
 
 
 Robert Velarde 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
I’ve been using Guerin’s Pharmacy for my mom’s prescriptions for years. The staff is always friendly and helpful. They go the extra mile by giving us a call when her medications are ready or when there’s a follow-up needed. It’s that kind of personal service that keeps us coming back. Highly recommend!
  
 
  
 
 
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 Alice DeLonge profile picture 
 
 
 Alice DeLonge 
 
 
 
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ALWAYS THERE FOR YOU FOLLOWING WORDS SUM IT UP KNOWLEDGE GUIDANCE FINDS A WAY COMPASSIATE
  
 
  
 
 
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 Darci Flowers profile picture 
 
 
 Darci Flowers 
 
 
 
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Staff is friendly and helpful. The pharmacy is quick. Lots of quirky, unique but interesting medicinal items available to purchase
  
 
  
 
 
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 Christian Chapman profile picture 
 
 
 Christian Chapman 
 
 
 
 Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google. 
Guerin’s is HOME. Oldest family run pharmacy in the state.They know you and take time to answer any questions you may have. I went there with my grandfather a one day my daughter will take her children there. Guerin’s’ IS Summerville.
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Serving Downtown Summerville, Ladson, Knightsville & Dorchester County

As South Carolina’s oldest operating pharmacy, Guerin’s Pharmacy has proudly served families across Dorchester and Berkeley counties since 1871. Located in historic Downtown Summerville, SC, our independent pharmacy provides personalized prescription dispensing, durable medical supplies, custom compounding, and walk-in immunizations for residents throughout Summerville, Ladson, Knightsville, Sangaree, and Lincolnville. Combine modern pharmacy care with friendly local service—visit our historic soda fountain or speak with our knowledgeable pharmacy team today.

Call or contact us to refill your prescription.

Contact Us
(843) 873-2531